Biosynthesis and Hydrolysis of Poly ( 7 - glutamic acid ) from BaciUizs

نویسندگان

  • Atsuo GoTo
  • Masao KuNioKA
چکیده

Poly(7-glutamic a id) (PGA) production ill Bacillas suhtitis IF03335 was studied. When citric acid as a carbon source was added to a glutamic acid medium containing L-glutamic acid and ammonium sulfate, a large amount of pure PGA wEs produced. On the other hand, when glucose was added to the glutamic acid medium, a by-preduct was produced, which seemed to be a polysaccharide. Moreoyer, the mode of hydrolysis was inyestigated with PGA in aqueous solutions at 80, 100, and 1200C by monitoring the time-dependent changes in the molecular weights. Hydrolytic degradation of PGA was found to proceed through a random chain scission.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

acid) from BaciUizs

Poly(7-glutamic a id) (PGA) production ill Bacillas suhtitis IF03335 was studied. When citric acid as a carbon source was added to a glutamic acid medium containing L-glutamic acid and ammonium sulfate, a large amount of pure PGA wEs produced. On the other hand, when glucose was added to the glutamic acid medium, a by-preduct was produced, which seemed to be a polysaccharide. Moreoyer, the mode...

متن کامل

Microbial synthesis of poly-γ-glutamic acid: current progress, challenges, and future perspectives

Poly-γ-glutamic acid (γ-PGA) is a naturally occurring biopolymer made from repeating units of l-glutamic acid, d-glutamic acid, or both. Since some bacteria are capable of vigorous γ-PGA biosynthesis from renewable biomass, γ-PGA is considered a promising bio-based chemical and is already widely used in the food, medical, and wastewater industries due to its biodegradable, non-toxic, and non-im...

متن کامل

Fabrication of TiO2 Hollow Spheres and its Application in Modification of Carbon Paste Electrode For Simultaneous Determination of Dopamine and Piroxicam in the Presence of Ascorbic acid

In this work we report preparation TiO2 hollow spheres and its application as an electrochemical sensor. Therefore the novel carbon paste electrode modified with TiO2 hollow spheres (TOHS), multi-walled carbon nanotubes (MWCNTs) and poly-glutamic acid (PGA) film (PGA/TOHS/MWCNTs/CPE) was used for simultaneous determination of dopamine (DA) and piroxicam (PRX) in the presence of ascorbic acid (A...

متن کامل

"Grafting-from" synthesis and characterization of poly (2-ethyl-2-oxazoline)-b-poly (benzyl L-glutamate) micellar nanoparticles for potential biomedical applications

Introduction: Recent advances in the field of poly (2-oxazolines) as bio-inspired synthetic pseudopeptides have proven their potential biomedical applications such as drug delivery and tissue engineering. Methods: In order to fabricate a biodegradable micellar nanoparticle of poly (2-ethyl 2-oxazoline)-b-poly (benzyl L-glutamate) or pEOx-b-pBLG, "grafting-from" synthesis approach was used invol...

متن کامل

Synthesis and Characterization of Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives from Diazomethane and HCl

Reaction of thionyl chloride with 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4- oxoquinoline-3-carboxylic acid 1 gave acid chloride 2. Compound 2 was reacted with glycine and D-glutamic acid to afford 2-(7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4- dihydroquinoline-3-carbonyl) aminopantandioicacid 3a and 2-(7-chloro-1-cyclopropyl-6- fluoro -4- oxo-1,4-dihydroquinoline-3-carbonyl)aminoacetica...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2018